
Guadalupe County Vacations & Trips from $342
Book a Hotel + Flight or Car together to unlock savings
Photo by Kate Cadwell
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Guadalupe County Vacation
Our Guadalupe County vacation packages provide an easy, affordable and immersive way to enjoy all that this unique destination has to offer. If it's nature and culture you're looking for, this is the place to be. Be sure to include Santa Rosa and Vaughn on your list of cities to explore when planning your trip to Guadalupe County. Expedia has flights, hotels and everything else you need to help you organize your own customized Guadalupe County vacation today.
Top destinations in Guadalupe County

Santa Rosa
The Latest Guadalupe County Vacation Packages
Price found within the past 48 hours. Click for updated prices.

Motel 6 Espanola, NM
Price was $357, price is now $342 per person
$342
per person
Jan 27 - Jan 31
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Santa Fe (SAF)
6.4/10 (515 reviews)
One of the cleanest motels I’ve been in a long time. The water was hot. It was good and they provided coffee. I will definitely stay here again.
Reviewed on Sep 30, 2025



Hampton Inn & Suites Los Alamos White Rock
Price was $419, price is now $377 per person
$377
per person
Feb 27 - Mar 2
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Santa Fe (SAF)
9/10 Wonderful! (670 reviews)
The room was clean, comfortable, and quiet. The staff was friendly and helpful. The amenities were good.
Reviewed on Nov 18, 2025
Find the Best Guadalupe County Vacation Packages
Guadalupe County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Albuquerque Intl. Sunport Airport (ABQ) |
Top Sights | Blue Hole, Santa Rosa Lake State Park and Blue Hole |
Guadalupe County Hotel Deals

La Quinta Inn & Suites by Wyndham Santa Rosa
2277 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $139 total per night from Dec 7 to Dec 8
$139 total
Dec 7 - Dec 8
Total with taxes and fees
9.2/10 Wonderful! (1,438 reviews)
nice
Reviewed on Dec 2, 2025

Days Inn & Suites by Wyndham Santa Rosa
2255 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $104 total per night from Jan 4 to Jan 5
$104 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
8.4/10 Very Good! (527 reviews)
Clean room. Arrived late and left early, so only slept a few hours then back on the road.
Reviewed on Dec 2, 2025

Hotel Blue 66, BW Signature Collection
2533 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $130 total per night from Dec 5 to Dec 6
$130 total
Dec 5 - Dec 6
Total with taxes and fees
8.2/10 Very Good! (162 reviews)
This is a clean and beautiful place. They are dog friendly, but don't have grass for them. I suggest they take 2 parking spot and covert them in a grass aarea
Reviewed on Nov 26, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
Other vacations you might like
- Top cities in Guadalupe County
- Vacations and getaways similar to Guadalupe County
- Best vacation destinations by month
- January Vacations and Deals
- February Vacations and Deals
- March Vacations and Deals
- April Vacations and Deals
- May Vacations and Deals
- June Vacations and Deals
- July Vacations and Deals
- August Vacations and Deals
- September Vacations and Deals
- October Vacations and Deals
- November Vacations and Deals
- December Vacations and Deals
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.




















