Guadalupe County Vacations & Trips from $559
Book a Hotel + Flight or Car together to unlock savings
Your Guadalupe County Vacation
Our Guadalupe County vacation packages provide an easy, affordable and immersive way to enjoy all that this unique destination has to offer. If it's nature and culture you're looking for, this is the place to be. Be sure to include Santa Rosa and Vaughn on your list of cities to explore when planning your trip to Guadalupe County. Expedia has flights, hotels and everything else you need to help you organize your own customized Guadalupe County vacation today.
Top destinations in Guadalupe County
Santa Rosa
The Latest Guadalupe County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Ohkay Casino Resort Hotel
Price was $749, price is now $615 per person
$615
per person
Oct 18 - Oct 22
found 11 hours ago
Roundtrip flight included
Dallas (DFW) to Santa Fe (SAF)
8/10 Very Good! (765 reviews)
I LIKED THE crab leg plate a bit not too meaty, should've gotten a burger. The room bed wise was good but noisy children next room too loud because of thin walls.
Reviewed on Aug 19, 2025
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
Price was $1,099, price is now $961 per person
$961
per person
Oct 6 - Oct 13
found 8 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Santa Fe (SAF)
8.8/10 Excellent! (709 reviews)
This was a convenient place to stay and call home for 4 days right outside of Los Alamos. The staff was friendly and helpful when we needed extra supplies.
Reviewed on Aug 23, 2025
The Inn at the Delta
Price was $748, price is now $657 per person
$657
per person
Oct 18 - Oct 22
found 11 hours ago
Roundtrip flight included
Dallas (DFW) to Santa Fe (SAF)
9.4/10 Exceptional! (1,000 reviews)
One less positive comment: a small part of the pillows or cases had a mold smell. Fortunately it was minimal.
Reviewed on Aug 5, 2025
Guadalupe County Hotel Deals
Comfort Inn Santa Rosa on Route 66
2524 Historic Route 66, Santa Rosa, NM
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $119 total per night from Sep 1 to Sep 2
$119 total
Sep 1 - Sep 2
Total with taxes and fees
Days Inn & Suites by Wyndham Santa Rosa
2255 Historic Route 66, Santa Rosa, NM
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $107 total per night from Sep 11 to Sep 12
$107 total
Sep 11 - Sep 12
Total with taxes and fees
8.4/10 Very Good! (457 reviews)
"Convenient location, close to viewed the Blue Hole. The only negative was the excessive smell of cleaner or whatever they do in the room."
Reviewed on Aug 25, 2025
La Quinta Inn & Suites by Wyndham Santa Rosa
2277 Historic Route 66, (Will Rogers Dr), Santa Rosa, NM
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $150 total per night from Sep 1 to Sep 2
$150 total
Sep 1 - Sep 2
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Other vacations you might like
- Top cities in Guadalupe County
- Vacations and getaways similar to Guadalupe County
- Best vacation destinations by month
- January Vacations and Deals
- February Vacations and Deals
- March Vacations and Deals
- April Vacations and Deals
- May Vacations and Deals
- June Vacations and Deals
- July Vacations and Deals
- August Vacations and Deals
- September Vacations and Deals
- October Vacations and Deals
- November Vacations and Deals
- December Vacations and Deals
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.